Abstract
We studied the structural and antimicrobial properties of copper oxide nanoparticles (CuO NPs) synthesized by a very simple precipitation technique. Copper (II) acetate was used as a precursor and sodium hydroxide as a reducing agent. X‐ray diffraction patter (XRD) pattern showed the crystalline nature of CuO NPs. Field emission scanning electron microscope (FESEM) and field emission transmission electron microscope (FETEM) demonstrated the morphology of CuO NPs. The average diameter of CuO NPs calculated by TEM and XRD was around 23 nm. Energy dispersive X‐ray spectroscopy (EDS) spectrum and XRD pattern suggested that prepared CuO NPs were highly pure. CuO NPs showed excellent antimicrobial activity against various bacterial strains (Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumonia, Enterococcus faecalis, Shigella flexneri, Salmonella typhimurium, Proteus vulgaris, and Staphylococcus aureus). Moreover, E. coli and E. faecalis exhibited the highest sensitivity to CuO NPs while K. pneumonia was the least sensitive. Possible mechanisms of antimicrobial activity of CuO NPs should be further investigated.
Highlights
Metal oxide nanoparticles (NPs) have been receiving considerable attention for their potential applications in optoelectronics, nanodevices, nanoelectronics, nanosensors, information storage, and catalysis
Structural property of CuO NPs was examined by X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM), and field emission transmission electron microscopy (FETEM) equipped with energy dispersive X-ray spectroscopy (EDS)
Pure CuO NPs was prepared by a simple precipitation method
Summary
Metal oxide nanoparticles (NPs) have been receiving considerable attention for their potential applications in optoelectronics, nanodevices, nanoelectronics, nanosensors, information storage, and catalysis. Among various metal oxide NPs, CuO has attracted particular attention because it is the simplest member of the family of copper compounds and shows a range of useful physical properties such as high temperature superconductivity, electron correlation effects, and spin dynamics [1, 2]. We reported synthesis, characterization, and antimicrobial activity of CuO NPs. CuO NPs were synthesized by a simple precipitation technique. Structural property of CuO NPs was examined by X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM), and field emission transmission electron microscopy (FETEM) equipped with energy dispersive X-ray spectroscopy (EDS). Characterization of CuO NPs. The crystalline nature of CuO NPs was carried out by XRD. The XRD pattern of CuO nanopowder was acquired at room temperature with the help of a PANalytical X’Pert X-ray diffractometer equipped with an Ni filtered using Cu Kα (λ = 1.54056 A ) radiations as an X-ray source. (b) Figure 2: (a) FESEM image of CuO NPs and (b) FETEM image of CuO NPs
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