Synthesis, Characterization, and Antibacterial Activity of Co(II), Ni(II), and Pd(II) Complexes with Bisdithiocarbamate and Cyclic Amines Ligands

Abstract

AbstractReaction of metal salts CoCl2·6H2O,NiCl2·6H2O and Na2[PdCl4] with thymine bisdithiocarbamate and uracil bisthiocarbamate in molar ratio 2:1 (metal/ligand) affords the presumably tetrahedral complexes [M2(dtc)(H2O)4Cl2] M; Co, Ni and square planer complexes [Pd(dtc)(H2O)4Cl2] dtc=tdtc, utdc. Dithiocarbamates (dtcs) behave as monodentate ligands. Reaction of [M2 dtc (H2O)4Cl2] M; Co (II), Ni (II), and Pd(II) with 1,10‐Phen.″ or 2,2′‐BiPy. (two equivalents) affords tetrahedral complexes of type [M2dtc(Amin)2Cl2] M; Co, Ni and square planer complexes [Pd2dtc(Amin)2Cl2], bis(dithiocarbametes) acts as a monodentate ligand and binds to the metal center through the soft sulfur atoms. Antibacterial activity of ligands and complexes is evaluated with two types of bacteria Staphylococcus aurous (gram‐positive) and Escherichia coli (gram‐negative). The complexes are characterized by physico‐chemical and spectroscopic methods.