Synthesis, characterisation and topological indices approach of hydrazone derivatives of disubstituted-2,6-diaryl piperidin-4-one, catalysed by CdO-SnO2 nanocatalyst

Abstract

The nanocatalyst CdO-SnO2 was effectively prepared using the co-precipitation method. Hydrazone derivatives of disubstituted-2,6-diaryl piperidin-4-one were synthesised using the nanocatalyst. All of the synthesised compounds were characterised using their IR and NMR spectra. The topological data from the molecular graphs was extracted using quantifiers from graph theory. These quantifiers, in turn, produced useful functions that made connections between different material attributes. These links were made possible by structural descriptors or, more frequently, graph invariants. Topological indices, which provide numerical functions that represent the molecular structure, were significant among the structural descriptors. Quantitative structure activity relations (QSAR) and quantitative structure property relations (QSPR) were made possible thanks to these indices. The calculated values were successfully used to determine the biological and chemical characteristics of the synthesised compounds.