Abstract
A series of some new class of 2-alkoxycarbonylamino-1,3,2-benzodiazaphosphole 2-oxides 4a–j were synthesised by reacting 3,4-diaminobenzophenone (3) with various dichlorophosphinyl carbamates (2) in dry toluene-tetrahydrofuran mixture (1:1) in the presence of triethylamine at 45–50°C. All the title compounds were evaluated for antimicrobial activity to determine their efficacy and were effective in suppressing the growth of bacteria and fungi. The chemical structures of the title products were characterised by IR, 1H, 13C and 31P NMR and mass spectral studies.
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