Synthesis, antibacterial study and corrosion inhibition potential of newly synthesis oxathiolan and triazole derivatives of 8-hydroxyquinoline: Experimental and theoretical approach

Abstract

Present work deals with the synthesis, antibacterial, and anticorrosion studies of novel oxathiolan and triazole compounds based on 8-hydroxyquinoline derivatives on mild steel in 1.0 M HCl. It is found that these heterocycles based on 8-hydroxyquinoline substituted compounds act as very good corrosion inhibitors and their inhibition performances influenced by the type of the 8-Hydroxyquinoline substituent used. In order to explore their potential biological activity, the “in vitro” antibacterial activity was investigated against [E. coli (ATCC35218), S. aureus (ATCC29213), V. parahaemolyticus (ATCC17802), and P. aeruginosa (ATCC27853)] using the agar disk diffusion method. The electrochemical behavior of different ratios of novel oxathiolan and triazole compounds based on 8-hydroxyquinoline derivatives was evaluated by EIS and Potentiodynamic polarization spectroscopy. Quantum chemical calculations (DFT) and Monte Carlo (MC) simulations were used to understand metal inhibitor interactions and the orientation of adsorption of studied inhibitors. Surface morphology and UV–visible spectroscopy (UV–vis) and scanning electron microscope (SEM) of the mild steel have also been studied.