Abstract
The rise in clinical significance of multi drug-resistant bacterial pathogens has directed us to synthesize a novel series of isatin derivatives and characterize them by IR, NMR, mass spectral, and elemental analysis. Compounds were evaluated for their preliminary in vitro antibacterial activity against Gram-positive (Staphylococcus aureus, Staphylococcus epidermis, Micrococcus luteus, Bacillus cereus) bacteria and were screened for antitubercular activity against Mycobacterium tuberculosisH37Rv strain by microplate alamar blue assay (MABA) method. Some synthesized compounds showed very good antibacterial and antitubercular activities.
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