Abstract
A novel series of Chalcones (2a-j) were prepared by reacting Furfuraldehyde and substituted ketones in alcohol medium in presence of NaOH. The Chalcones undergoes selective cyclization with Benzhydrazide (1) in glacial acetic acid medium to yield the title compounds 1,3,5-trisubstituted Pyrazolines (3a-j). All the newly synthesized compounds were evaluated for their In-Vitro antibacterial and antifungal activities. The new compounds were assigned on the basis of 1H-NMR, IR, Mass spectral data and elemental analysis. Some of the tested compounds showed potent activity against antifungal organism A.fumigatus.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
