Synthesis and studies of bissydnone sulfonamides based on 4,4’-diaminodiphenyl methane

Abstract

3,3’-(4,4’-Diphenyl)bissydnonyl methane ( 5 ) was synthesized and subjected to chlorosulfonation followed by amination resulted in to formation of 3,3’-(methylenedi-1,4-phenylene)bis[4-{(4-substituted-amino)sulfonyl} sydnone ( 7a-j ). The structure of the newly synthesized compounds was checked by spectral data and purity of the compounds was checked by elemental analysis as well as thin layer chromatography. Some compounds showed excellent activity against gram positive and gram negative bacterial strain.