Synthesis and Structure of Dimeric Copper (I) Complex from Bis[(2,2’)-dimethyl 2,2’-(1,10-phenanthroline-2,9-diyl) bis(methan-1-yl-1-ylidene)-bis(hydrazinecarbo dithioate)

Md Arifuzzaman,Mohamad A Ali,Aminul H Mirza,Tasneem A Siddiquee,Mohammad R Karim

doi:10.4236/csta.2013.24022

Abstract

Metal complex, bis[(2,2’)-dimethyl 2,2’-(1,10-phenanthrline-2,9-diyl)bis(methan-1-yl-1-ylidene)-bis(hydrazinecarrbo dithioate)copper(I)], was synthesized from the reaction of Schiff base, (2,2’)-dimethyl 2,2’-(1,10-phenanthroline-2,9-diyl)bis(methan-1-yl-1-ylidene)-bis(hydrazinecarbo dithioate) and CuCl2 at reflux condition in methanol. The copper centers of the complex appear to be reduced. This probably was facilitated by in situ oxidative formation of disulfide bond at the uncomplexed ligand moieties. Single crystal X-ray diffraction analysis reveals the distorted tetrahedral geometry around the copper centers. This compound crystallizes in the triclinic space group, P-1 with crystallographic parameters: a = 10.006(3) ?, b = 13.272(3) ?, c = 22.123(6) ?, α = 85.656(6)°, β = 81.656(6)°, γ = 73.097(5)°, μ = 1.223 mm-1 , V = 2779.5(13) ?3, Z = 2, Dc = 1.437 Mg/m3, T = 293 (2) K.

Highlights

Schiff bases bearing bidentate N,N’ chelating agents such as 1,10-phenanthroline have been used extensively as a ligand in both analytical and preparative coordination chemistry as well as in the preparation of many mixed-ligand complexes [1]
Metal complexes derived from 1,10-phenanthroline have been found to be widely used in areas such as molecular catalysis, solar energy conversion, calorimetric analysis, herbicides, molecular recognition, self-assembly, antineoplastic agents and nucleic acid probes [3]
It has been found that copper(II) complexes of ferrocene(Fc)-conjugated reduced Schiff base of L-tyrosine are cytotoxic in HeLa and MCF-7 [7]. 1,10-phenanthroline and its copper (I and II) complexes showed interesting magnetic, electronic and redox process [8]

Summary

Introduction

Schiff bases bearing bidentate N,N’ chelating agents such as 1,10-phenanthroline (phen) have been used extensively as a ligand in both analytical and preparative coordination chemistry as well as in the preparation of many mixed-ligand complexes [1]. These complexes have interesting physiochemical properties and have high potential as antibacterial, antifungal and chemotherapeutic agents [2]. The key feature of 1,10-phenanthroline is π-electron deficient nitrogen which stabilizes various metal complexes in lowered oxidation states [4]. 1,10-phenanthroline and its copper (I and II) complexes showed interesting magnetic, electronic and redox process [8] It has been found that copper(II) complexes of ferrocene(Fc)-conjugated reduced Schiff base of L-tyrosine are cytotoxic in HeLa (human cervical cancer) and MCF-7 (human breast cancer) [7]. 1,10-phenanthroline and its copper (I and II) complexes showed interesting magnetic, electronic and redox process [8]

Methods

Results

Conclusion