Synthesis and structural characterization of new oligonucleotide and nucleoside analogues as pharmacological tools

Abstract

Short abstract pag. i Long abstract pag. ii CHAPTER 1 “General Introduction” 1.1 Synthesis and structural characterization of oligonucleotide (ON) analogues pag.1 1.2 Synthesis of nucleoside and nucleotide analogues pag.3 CHAPTER 2 “Synthesis of TFO (Triplex Forming Oligonucleotides) containing a 3’-3’ polarity inversion site conjugated to moieties (acridine residue) capable to stabilize the triple helix complexes or to supply particular biological activities”