Synthesis and Self-Assembly of a Novel Cyclic Hexapeptide and Octapeptide

Abstract

In recent decades, cyclic peptides have attracted great attention due to their unique properties. In this paper, novel cyclic hexapeptide (6) and octapeptide (9) were designed and synthesized using liquid phase synthesis methodology. They were characterized by FT-IR, 1HNMR spectroscopy, LC-MS, scanning electron microscopy (SEM) and atomic-force microscopy (AFM). We have used these cyclic peptides as novel building blocks to generate porous materials by self-assembly.