Abstract
The methylation of 2-formyl-3-hydroxyindole was studied, and the sequence of introduction the methyl groups was traced by1H NMR spectroscopy. The O-methyl, N-methyl, and N,O-methyl derivatives of 2-formylindole, and also the O-methyl and N-methyl derivatives of 2-methyl-3-ethoxycarbonyl-4-hydroxypyrrole were synthesized. Novel derivatives of indolyl- and pyrrolylacrylic acids were obtained on the basis of some O- and N,O-substituted aldehydes of the indole and pyrrole series.
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