Abstract
A novel bridged nucleic acid (BNA) analogue, 2′- O,4′- C-methyleneoxymethylene bridged nucleic acid (2′,4′-BNA COC), was synthesized and incorporated into oligonucleotides. The 2′,4′-BNA COC modified oligonucleotides showed high binding affinity with an RNA complement and significant enzymatic stability against snake venom phosphodiesterase.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Paper version not known
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
