Abstract
The condensation of 2-amino-3-hydroxypyridine with 2-furoyl chloride according to Ladenburg gave 2-(2-furyl)[1,3]oxazolo[4,5-b]pyridine which was subjected to electrophilic substitution reactions with nitric acid, bromine, hexamethylenetetramine, acetic anhydride, and benzoic acid. In all cases, the electrophile entered exclusively the 5-position in the furan ring. Treatment of the title compound with methyl iodide afforded the corresponding quaternization product at the N4 atom, whereas no Chichibabin amination was observed.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
