Abstract

Oxygen bridged highly functionalized novel calix[2]arene[2]triazine derivatives were synthesized from 2,6-pyridinedimethanol and cyanuric chloride. All the synthesized oxacalixarenes showed an absorbance band between 315-339 nm and two emission bands at 269-272 nm and 289-339 nm. All the oxacalixarenes exhibited quasireversible oxidation reduction signals in cyclic voltammetry. The binding properties of the oxacalixarenes towards calf thymus DNA (CT-DNA) were investigated by viscosity measurements, UV-VIS and circular dichorism studies and the oxacalixarenes possess comparable antibacterial activity against B. cereus, S. aureus and E. coli as supported by docking studies.

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