Abstract

A series of Oxadiazole derivatives ( 4 a - d ) have been synthesized from (2 , 4, 5 - triphenyl - imidazole - 1 - yl) - acetic acid hydrazide under various reaction condition s . Elemental analysis, IR, 1 H NMR and mass spectral data confirmed the structure of the newly synthesized compounds. All the s ynthesized Oxa diazole derivatives have been investigated for their anti - inflammatory activity show ing moderate to good activity .

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