Abstract
Opening of the oxirane ring in 1-oxiranylmethylindoles yielded new indole derivatives containing 1,2-amino alcohol residues at the nitrogen atom. Compounds were studied in vitro in relation to various types of pharmacological activity typical of this class of compounds, including receptor (5-HT2, 5-HT3, P2Y1-ergic, κ-opioid), antiaggregant, hemorheological, antiarrhythmic, and antioxidant activities.
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