Abstract
A novel water soluble cage sulfonamides was prepared and their neurotropic effects were evaluated. In vivo tests showed high level of analgesic and tranquilizing activity of trans- N-(bicyclo[2.2.1]hept-5-en- endo -2-ylmethyl)-4-hydroxytetrahydrothiophene-3-sulfonamide-1,1-dioxide, greater than well known sodium metamizole, used as the internal standard. Stereochemical structure of title compounds was confirmed using the NOE and 2D NMR experiments.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
