Abstract

AbstractA series of new 4‐aryloctahydropyrido[1,2‐c]pyrimidine‐1,3‐diones 6a,b,d‐h and j were synthesized by intramolecular cyclization of α‐aryl‐α‐(1‐ethoxycarbonyl‐2‐piperidyl)‐acetamide derivatives 5a,b,d‐h and j. The structures of compounds were determined by 1H and 13C nmr spectroscopy. Nmr and X‐ray diffraction data indicate that the configuration at the C4, C4a stereocenters constitute RR and SS pair.

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