Abstract
The new uridine-containing derivative of p-tert-butylcalix[4]arene 5,11,17,23-tetra-tert-butyl-25,26,27-trihydroxyl-28-oxyuridinecalix[4]arene (CU) was synthesized and characterized by1H NMR,13C NMR, IR, EI-MS, and ESI-MS spectra. By the aid of UVvis spectra, the molecular recognition of CU was studied. The hypochromic effect in UVvis spectra showed the obvious molecular recognition of CU to ATP. This recognition is actually the hydrogen bond interaction between the uracil group of CU and the base radical of ATP. The association constant between CU and adenine was determined by UV titration at low concentrations.Key words: calixarene, uridine, molecular recognition, UVvis spectra.
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