Abstract

Cyclohexanecarboxylic acid (6A-deoxy-β-cyclodextrin-6A-C-yl)-amide (CHC-βCD) was synthesized via an aza-Wittig reaction and found to form in water, a temperature-independent intramolecular complex with its own cyclohexyl moiety. The analysis was based on data from 2D and variable-temperature NMR spectroscopy. The self-inclusion behavior of peracetylated CHC-βCD (PACHC-βCD) in chloroform was also investigated.

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