Abstract
AbstractSeventeen unsymmetrical bis‐arylalkyl ketones were synthesised and their insecticidal activities against Musca domestica, Locusta migratoria, Drosophila melanogaster, Dysdercus cingulatus, Aedes aegypti and Tetranychus urticae were tested. The synergistic effect of piperonyl butoxide on the activities of some of the new ketopyrethroids against Musca domestica was also determined. Several structural variations, including substituent exchange in the aryl moieties, the position of the ketone function and increase or decrease of the length of the carbon chain connecting the two aryl moieties, were made in order to examine the structure‐activity relationship. All biological activities were compared with the activity of the ether pyrethroid 2‐(4‐ethoxyphenyl)‐2‐methylpropyl 3‐phenoxybenzyl ether (MTI‐500).
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