Abstract
AbstractThe objective of this study is synthesis, characterization, and evaluation of a novel crosslinker to form spheroids. Our approach was based on the crosslinking of cell membrane using a polymeric crosslinker via hydrophobic interaction. A crosslinker poly(ethylene glycol) derivative with oleyl groups as hydrophobic group at both ends was synthesized, and then characterized with gel permeation chromatography and Fourier‐transform infrared spectroscopy. Furthermore, cell culture experiments were performed to confirm spheroid formation. Spheroids were successfully obtained when the crosslinker was added to cell suspension. This polymeric crosslinker was useful in the formation of cell spheroid.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
