Abstract
Synthesis and evaluation of ?-hydroxy fatty acid-derived heterocyclic compounds with potential industrial interest
Highlights
The reaction of 2-hydroxyheptadecanoyl chloride (2) and anthranilic acid gave 2-(1-hydroxyheptadecyl)-4H-3,1benzoxazin-4-one (3) which was used as starting material to synthesize some condensed and non-condensed heterocyclic compounds by a reaction with nitrogen nucleophiles
They have good storage stability in detergents (Mohamed et al, 2003). This led us to synthesize 2-(1hydroxyheptadecyl)-4H-3,1-benzoxazin-4-one (3) and several quinazoline derivatives which may have pharmaceutical and industrial applications. This encouraged us to synthesize a novel group of nonionic surface active agents containing these nuclei
These compounds have a double function as antimicrobial and as surface active agents which may serve in the manufacturing of drugs, cosmetics, pesticides or as antibacterial and/or antifungal agents
Summary
Synthesis and evaluation of α-hydroxy fatty acidderived heterocyclic compounds with potential industrial interest. This led us to synthesize 2-(1hydroxyheptadecyl)-4H-3,1-benzoxazin-4-one (3) and several quinazoline derivatives which may have pharmaceutical and industrial applications This encouraged us to synthesize a novel group of nonionic surface active agents containing these nuclei. These compounds have a double function as antimicrobial and as surface active agents which may serve in the manufacturing of drugs, cosmetics, pesticides or as antibacterial and/or antifungal agents. The surface properties such as surface and interfacial tension, cloud point, foaming height, wetting time, and emulsification power were determined.
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