Abstract
For the first time, a new acyl ureide of the anticonvulsant and anti-alcohol drug galodif (3-chlorobenzhydryl urea) with succinic acid was obtained and studied. The synthesis was carried out by the acylation of galodif with succinic anhydride in presence of certain acids. Unlike galodif, which is practically insoluble in water, the resulting benzhydryl ureide is soluble in aqueous media and can potentially exhibit greater bioavailability and can be used as a liquid dosage form and prodrug with prolonged action.
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