Synthesis and crystal structure of the one-dimensional chain triphenyltin compound bridged by 5-chloro-6-hydroxynicotinic acid

Abstract

Reaction of 5-chloro-6-hydroxynicotinic acid with Ph3SnCl and sodium ethoxide in 1:1:1 stoichiometry yielded triphenyltin compound. This compound has been characterized by single crystal X-ray diffraction, elemental analysis, IR and 1H NMR spectroscopy. In the molecular structure of the title compound, the tin atoms are five-coordinated in a distorted trigonal bipyramidal geometry. The resulting structure is 1D linear polymer through an interaction between the O atoms of phenolic hydroxide and tin atoms of an adjacent molcule. The compound exhibit high antitumor activity.