Synthesis and Crystal Structure of (E)-2-(2-hydroxyphenyl)-3-((1-(2-hydroxyphenyl)ethylidene)amino)-2,3-dihydroquinazolin-4(1H)-one

Abstract

The title hydrazone compound contains bicyclic heterocyclic ring, was synthesized by simple stepwise condensation of 2-hydroxyacetophenone with 2-aminobenzoylhydrazide followed by the addition of salicylaldehyde in alcohol under refluxing condition. The compound was characterized by spectroscopic techniques, namely, FT-IR, 1H-NMR, mass and UV-Vis. The structure of this compound was determined by X-ray crystallographic method. The compound crystallized in the Orthorhombic crystal system with space group Pbca and a=15.3289(9) Å, b=14.6287(8) Å, c=16.5451(10) Å. In the crystal structure of the compound both intra- and inter-molecular hydrogen bonds are are shown to exist.