Abstract

The first synthesis of an O-silylated derivative of a hexahomotriazacalix[3]arene has been achieved using 1-(trimethylsilyl)imidazole (TMSIM), 1,1,1,3,3,3-hexamethyldisilazane (HMDS), or bis(trimethylsilyl)trifluoroacetamide (BSTFA) in acetronitrile. The cone isomer was formed selectively using TMSIM and HMDS; whereas a cone/partial cone mixture was obtained using BSTFA.

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