Synthesis and Characterization of Thiazepine/Benzothiazepine Derivatives Through Intramolecular C‐2 Ring Expansion Pathway

Abstract

A facile and highly efficient one‐pot synthesis of novel thiazepine and benzothiazepine derivatives was established by ring expansion. With a greener methodology (ultrasonication), a polysubstituted ring system with the thiazepine core moiety can be easily synthesized from simple and easily available reactants in good yields. Moreover, the synthesized compounds show fluorescence and also antioxidant activity.