Abstract

The phosphate mineral struvite is basically formed in urinary tracks and kidney. One of the analogous compounds of struvite is potassium magnesium phosphate hexahydrate (KMgPO4·6H2O), known as struvite-k crystal and found in animal urinary calculi. In the present investigation, struvite-k crystals were grown by single diffusion and double diffusion techniques in agar gelmedium. The grown crystals were analyzed by optical microscopy, scanning electron microscopy (SEM), fourier transform infrared (FTIR) spectroscopy, X-ray diffraction (XRD), energy dispersive X-ray analysis (EDXA) and thermogravimetric analysis (TGA). Optical microscopy and SEM exhibited the different morphologies. The FTIR spectra revealed the presence of water molecules, stretching and bending vibrations of phosphate (PO4) ions. However the powder XRD results from the crystalline nature. Elemental composition in the crystal was obtained by EDXA, while 36.89% weight loss of water molecules is observed in TGA study.

Highlights

  • Urolithiasis is the formation of urinary calculi, known as renal kidney stone, which is one of the serious and debilitating problems in the world [1]

  • The renal stones are the product of pathological bio mineralization in urinary system which is composed of several components and cannot be contributed to any single factor [3]

  • The chemical composition shows that, growth depends on diet, social class, age, sex of the person and on climatic and environmental conditions [4] [5]

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Summary

Introduction

Urolithiasis is the formation of urinary calculi, known as renal kidney stone, which is one of the serious and debilitating problems in the world [1]. Hydroxyapatite [6], carbonate apatite [7] and brushite [8] are the common constituents of calciumphosphate crystals, whereas ammonium magnesium phosphate hexahydrate (NH4MgPO4∙6H2O) known as struvite and magnesium hydrogen phosphate trihydrates (MgHPO4·3H2O), i.e. newberyite, is the common constituents of magnesium phosphates crystals. They are reported in vesicle as well as renal calculi of adults [1] [9] [10] and children [11]-[13]. The struvite-k crystals were grown in agar gel at ambient temperature and were characterized by optical microscopy, scanning electron microscopy (SEM), fourier transform infrared (FTIR) spectroscopy, X-ray diffraction (XRD), energy dispersive X-ray analysis (EDXA) and thermogravimetry analysis (TGA)

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