Abstract
In this work, the preparation of novel biocompatible polyurethane (PU) elastomers were carried out using curcumin and 1,4-butanediol (1,4-BDO) via step growth polymerization reaction of hydroxyl terminated polybutadiene (HTPB), toluene diisocyanate (TDI) and chitin to improve the biocompatibility, antibacterial and antioxidant properties of PU elastomers. Five samples were synthesized by varying moles ratio of curcumin and 1,4-BDO. The structural study of blends was done by FTIR spectroscopy which confirmed the incorporation of curcumin and 1,4-BDO into the polyurethane matrix. TGA analysis of polyurethane (PU) blends showed good thermal stability with 0.25 M curcumin and 1.75 M 1,4-BDO. Measurements of antibacterial properties were done via agar diffusion method which showed outstanding potential against selected strains of bacteria. The results revealed that biocompatibility, antibacterial and antioxidant potential of purposed polyurethanes elastomers were improved by the incorporation of curcumin which might be the precursor of biomedical applications. Collectively, this work is a footstep towards the synthesis of innovative biocompatible materials which made it suitable for biological applications.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: International Journal of Biological Macromolecules
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
