Abstract
The mixed ligand complexes of Zn(II) with 4,4-bipyridine and some organic acids or amino acids were prepared in the solid form and characterized by elemental analysis, conductivity, magnetic moment measurement, IR, 1H-NMR, 13C-NMR and FAB+ mass studies. To study anti-inflammatory and analgesic activities of these complexes, some Swiss albino mice of 5-7 weeks old were taken. One dose of the test compounds of 10 mg/kg was selected throughout the research work. The anti-inflammatory activity of the test compounds were determined by carrageenan induced mice paw edema inhibition method. The analgesic activity was determined by acetic acid induced writhing methods. These three compounds showed positive effects as anti-inflammatory and analgesic agents. Anti- inflammatory and analgesic activities of the test compounds at 50 mg/kg were quite comparable to those of standard drugs at 10 mg/kg. Keywords: Zinc; Organic acids; 4, 4'-Bipyridine; Anti-inflammatory; Analgesic activity. © 2014 JSR Publications. ISSN: 2070-0237 (Print); 2070-0245 (Online). All rights reserved. doi: http://dx.doi.org/10.3329/jsr.v6i2.16994 J. Sci. Res. 6 (2), 309-318 (2014)
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
