Abstract
Background: Many organoselenium compounds are well known for their applications in various fields. However, some of the organoselenium compounds, like selenosemicarbazones, due to difficulties in their synthesis are not much explored. Herein, we present the synthesis and characterization of five different new selenosemicarbazones. Objective: The study aimed to carry out the synthesis and characterization of novel selenosemicarbazones, a type of Schiff bases. Methods: Selenosemicarbazones are synthesized in a single step, i.e., acid-catalyzed condensation reaction between ketones and hydrazine hydrate in the presence of potassium selenocyanate (KSeCN). Results: Butyrophenone, 4-phenyl 2-butanone, 2-acetonaphthone, 4-nitroacetophenone and menthone were reacted with in-situ generated selenosemicarbazide, which led to the formation of respective selenosemicarbazones. These organoselenium derivatives of Schiff bases have been characterized by mass spectrometry, proton, carbon and selenium NMR. Conclusion: The yields of synthesized butyrophenone, 4-phenyl 2-butanone, 2-acetonaphthone, 4- nitroacetophenone, and menthone selenosemicarbazones varied in between 44 to 65%. The synthesis strategy involved one-pot synthesis of selenosemicarbazone without isolation of toxic selenosemicarbazide.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
