Abstract

Novel poly(lactic acid)-conjugated CdTe quantum dots (PLA-conjugated CdTe QDs) were synthesized by surface grafting through living polymerization of lactic acid O-carboxyanhydride (LacOCA) on CdTe quantum dots. The PLA-conjugated CdTe QDs were spherical nanoparticle, and they were relatively uniform with a diameter of 4.5nm. The PLA-conjugated CdTe QDs showed strong blue fluorescence emission in vitro, and their luminescence was stable in aqueous solution for more than 60d. Furthermore, these QDs showed low cytotoxicity towards HaCaT cells in vitro. The results suggest potential applications for PLA-conjugated CdTe QDs in biological staining and diagnostics.

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