Synthesis and characterization of plate like high surface area MgO nanoparticles for their antibacterial activity against Bacillus cereus (MTCC 430) and Pseudomonas aeruginosa (MTCC 424) bacterias

Abstract

• A high surface area and plate like MgO were synthesized by simple precipitation method. • MgO showed good antibacterial activity against both Bacillus cereus and Pseudomonas aeruginosa bacterias. • Pseudomonas aeruginosa (MTCC 424) was slightly resistant compared to Bacillus cereus (MTCC 430). • The effect of morphology, surface area, and particle size on antibacterial activity was analysed. In the present work high surface area MgO nanoparticles were synthesized by simple precipitation method without using any directing agent or capping agent. In this regard various experimental conditions required to achieve high surface area MgO nanoparticles have been addressed in this work. The experimental conditions namely, pH, calcination temperature, digestion temperature, digestion temperature and nature of precursor and precipitating agent, collectively produce high surface area MgO nanoparticles. The optical bandgap, functional group identification, the crystalline phase, surface morphology of MgO nanoparticles were obtained from UV– Vis, FTIR, XRD, SEM, and HRTEM techniques. The optical bandgap was found to be 5.8 eV. With the help of BET technique both specific surface area and the average pore diameter values were obtained and were found to be 246.95 g/m 2 and 6.721 nm respectively. The antibacterial activity of MgO nanoparticles was tested against Bacillus cereus (MTCC 430) and Pseudomonas aeruginosa (MTCC 424) bacterias. The material exhibited good antibacterial activity against both bacterias. A dosage concentration of 80 mg/ml concentration was sufficient to inhibit the bacterial growth. Further analysed the effect of particles size, surface area, optical bandgap, and morphology on antibacterial activity of MgO nanoparticles.