Abstract
In this report, we describe the synthesis and characterization of photosensitive poly( l-lactide) with a pendent cinnamate group. α,ω-Dihydoxy terminated poly( l-lactide) (PLLA-diol) [molecular weights (MW); 2000, 4000 and 9000 g/mol ] was chain-extended with a diacyl chloride of 5-cinnamoyloxyisophthalic acid (ICA) to obtain high-molecular-weight photocrosslinkable poly( l-lactide)s (ICA/PLLA). The resulting polyesters were characterized by proton nuclear magnetic resonance spectroscopy, gel permeation chromatography, ultraviolet–visible spectroscopy, differential scanning calorimetry, thermomechanical analysis and thermogravimetry. The glass transition temperature ( T g), the melting temperature ( T m) and the degree of relative crystallinity ( X c) of ICA/PLLAs increased with the increasing MW of the PLLA-diols. The photosensitive ICA/PLLAs were irradiated with a 400 W high-pressure mercury lamp ( λ > 280 nm) for various times to produce the PLLA gel films without a photoinitiator. The crosslinking rate monitored by a UV–vis spectrum decreased with the increasing MW of the PLLA-diols. The crosslinking of the ICA/PLLA −4000 film enhanced the T g slightly and the tensile strength and Young’s modulus significantly, while reduced the T m and X c. The enzymatic degradation was measured by the weight loss of the films in a phosphate buffer solution with proteinaze-k. The crosslinking of the films decreased markedly the degradation rate.
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