Synthesis and Characterization of Per‐3,6‐anhydro Cyclodextrins

Abstract

Cyclodextrin derivatives such as 1, which contain glucopyranose units in 1C4 conformation, were synthesized from per(6-O-tosyl)-β-cyclodextrin. The pure α-cyclodextrin derivative (with six sugar units) was obtained from per(2,3-O-benzoyl-6-O-tosyl)-α-cyclodextrin. Both anhydrodextrins are potential molecular receptors in which the cavity is lined with hydroxyl groups.