Abstract
In the present study, a novel series of N5-(3-substituted benzylidene)-N4-phenyl pyrimidine-4,5-diamine / N5-(2- substituted benzylidene)-N2,N2-dimethyl-N4-phenyl pyrimidine-2,4,5-triamine were synthesized by using the starting ingredient formimidamide/ 4-(dimethylamino) benzimidamide and it was characterized by IR, 1H NMR and Mass spectral analyses. The synthesized compounds aiming towards the development of potential antimicrobial agents in this connection the screening of structures of the synthesized scaffolds were possessing their antimicrobial activity against G+ve bacteria Stap.aureus, Stap.epidermidis, Micr.luteus and Baci.cereus, G-ve bacteria Ech.coli, Pseu.aeruginosa & Kleb.pneumoniae and fungi Asp.niger & Asp.fumigatus. Among all the synthesized compounds four derivatives were showed the highest significant zone of inhibition towards G+ve, G-ve bacteria and fungi microbial growth.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
