Abstract
Hydrogels wound dressings have enormous advantages due to their ability to absorb high wound exudate, capacity to load drugs, and provide quick pain relief. The use of hydrogels as wound dressings in their original form is a considerable challenge, as these are difficult to apply on wounds without support. Therefore, the incorporation of polymeric hydrogels with a certain substrate is an emerging field of interest. The present study fabricated cellulose hydrogel using the sol–gel technique and reinforced it with nonwoven cotton for sustainable wound dressing application. The nonwoven cotton was immersed inside the prepared solution of cellulose and heated at 50 °C for 2 h to form cellulose hydrogel–nonwoven cotton composites and characterized for a range of properties. In addition, the prepared hydrogel composite was also loaded with titania particles to attain antibacterial properties. The Fourier transform infrared spectroscopy and scanning electron microscopy confirmed the formation of cellulose hydrogel layers inside the nonwoven cotton structure. The fabricated composite hydrogels showed good moisture management and air permeability, which are essential for comfortable wound healing. The wound exudate testing revealed that the fluid absorptive capacity of cellulose hydrogel nonwoven cotton composite was improved significantly in comparison to pure nonwoven cotton. The results reveal the successful hydrogel formation, having excellent absorbing, antimicrobial, and sustainable properties.
Highlights
Traditional wound dressings such as bandages, gauze, and cotton pads [1] are often used to cover the wound [2]
Scanning Electron Microscopy (SEM) images of pure nonwoven cotton fabric, cellulose hydrogel reinforced with nonwo
SEM images of pure nonwoven cotton fabric, cellulose hydrogel reinforced with nonwoSEM images of pure nonwoven cotton fabric, cellulose hydrogel reinforced with nonwoven ven cotton cottonfabric, fabric,and andTiO
Summary
Traditional wound dressings such as bandages, gauze, and cotton pads [1] are often used to cover the wound [2]. Nonwoven fabrics are manufactured by direct conversion of fibers into fabrics, eliminating the process of yarn manufacturing [48] Owing to their excellent absorbing and highly porous properties, nonwoven fabrics are among the best options as supporting materials for textile-based hydrogel wound dressings [49]. Cotton is a naturally available, soft, flexible, and durable fiber that exhibits excellent water-absorbing properties due to the presence of hydrogen bonding in the cellulose structure [50,51]. The combination of cotton fiber nonwoven and MCC-based hydrogel is one of the potential choices for wound dressings with mediumto-heavy amounts of exudates. The loading of TiO2 makes the composite antibacterial for wounds
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