Abstract
AbstractIn this paper we report the synthesis and characterization of novel trans platinum(II) complexes of general formula trans‐[PtCl2(L)(PPh3)], where L is NH2CH(CH3)CH2CH3 (complex 1), (R)‐NH2CH(CH3)CH2CH3 (complex 2), (S)‐NH2CH(CH3)CH2CH3 (complex 3) and NH2CH(CH3)2 (complex 4). The new complexes contain phosphane ligands trans to the amine group. X‐ray crystal structure determinations of complexes 1 and 3 confirmed their trans configurations. The cytotoxic activity of these complexes have been evaluated and compared with the activity of trans platinum complexes already viewed as potential drugs. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003)
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
