Abstract
A series of polyether substituted salicylaldehyde derivatives OHCC6H3OH-2-OR-3 [R = CH2-(CH2OCH2)(n)CH(2)OR', n = 1, 4 and R' = Me; n = 5 and R'= H] have been synthesised and used to prepare the polydentate ligands HN[(CH2CH2NHCH2CH2N=CHC6H3OH-2-OR-3](2), HN[CH2CH2NHCH2CH2NHCH2C6H3-OH-2-OR-3](2) and HN[CH2CH2N=CHC6H3OH-2-OR-3](3); a preliminary evaluation has been made of the potential use of their gadolinium complexes as contrast agents for diagnostic Magnetic Resonance Imaging.
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