Abstract
A Schiff base ligand, 3-((6-amino-1,6-dihydropyridin-2-yl)imino)indolin-2-one, was synthesized by condensing isatin with 2,6-diaminopyridine in this study. Elemental analysis, NMR spectroscopy, and infrared spectroscopy enabled confirmation of the structure of the pyridineincorporated ligand. Additional coordination compounds of this ligand with Mn(II), Co(II), Ni(II), Cu(II), Zn(II), and Cd(II) metals were synthesized with metal-to-ligand proportions verified through trace elemental examinations using CHN. Various spectroscopic techniques including UV-visible absorption spectrophotometry, IR spectrophotometry, electrical conductivity quantifications, melting point determinations, and magnetic susceptibility analyses facilitated characterization of the produced complexes. The antimicrobial potential of the organic ligand and inorganic complexes was screened against Bacillus subtilis and Staphylococcus aureus bacterial strains through the agar disc diffusion technique. Both the uncoordinated ligand and metal-ligand coordination compounds displayed appreciable antibacterial effects on the tested microorganisms. Tetrahedral configurations were proposed for all prepared complexes based on combined analytical and spectroscopic evidence.
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