Abstract

The new compounds 6,6a‐dihydro‐2,3‐dimethoxy‐9‐nitro–11bH benzo [C]‐fluoren 5,7‐dione, 6,6a‐dihydro‐2,3‐dimethoxy‐9‐chloro–11bH benzo[C]‐fluoren‐5,7‐dione and 6,6a‐dihydro‐2,3‐dimethoxy‐9‐fluoro–11bH benzo[C]‐fluoren‐5,7‐ dione were synthesized in high yields. They are analogues of naturally occurring lignan podophyllotoxin which exhibits anticancer activity. They are very essential to study anticancer activity.

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