Synthesis and Characterization of New Bidentate Schiff Base Ligand Type (NO) Donor Atoms Derived from Isatin and 3-Amino Benzoic Acid and Its Complexes with Co(II), Cu(II), Cd(II) and Hg(II) Ions

Heam Hadi Alkam

doi:10.30526/30.3.1610

Abstract

New bidentate Schiff base ligand (L) namely [(Z)-3-(2-oxoindolin-3ylildeneamino)benzoic acid] type (NO) was prepared via condensation of isatin and 3-amino benzoic acid in ethanol as a solvent in existence of drops of (glac. CH3COOH). The new ligand (L) was characterized base on elemental microanalysis, FT-IR, UV-Vis, 1H-NMR spectra along with melting point. Ligand complexes in general formula [M(L)2Cl2]. H2O, where: MII = Co, Cu, Cd, and Hg; L= C15H10 N2O3 were synthesized and identified by FT-IR, UV-Vis, 1H-NMR (for Cd complex only) spectra, atomic absorption, chloride content along with molar conductivity and magnetic susceptibility. It was found that the ligand behaves as bidentate on complexation via (N) atom of imine group and (O) atom of carbonyl group of five member ring. The electronic spectral data and µeff values (Co, Cu) of the complexes exhibited octahedral geometry around CoII, CuII, CdII, HgII metal ions. The results of antibacterial activity showed that only Hg(II) complex has high activity (35 mm) for staphylococcus aureas.

Highlights

1H-indol-2,3-dione (Isatin) is an important substrate, where it can be used for preparing of a wide variety of heterocyclic compounds, such as indoles and a raw material for drug synthesis
Due to its cis α-dicarbonyl moiety, is a good substrate for complexes formation, either alone or deprotonated, isatin was found in mammalian tissues[1]
The elemental micro analysis results for the ligand and their metal complexes are in a good agreement with the calculated values

Summary

Introduction

1H-indol-2,3-dione (Isatin) is an important substrate, where it can be used for preparing of a wide variety of heterocyclic compounds, such as indoles and a raw material for drug synthesis. In this paper we synthesized new Schiff base from reacted isatin and 3-aminobenzoic acid and its complexes with Co(II), Cu(II), Cd(II) and Hg(II). Electronic spectra were measured in region (200 – 1000 nm) for 10-3M solution in DMSO at 25 ̊C using

Results

Conclusion