Abstract
It is well known that graphene oxide (GO) possesses antibacterial properties towards both Gram-positive and Gram-negative bacteria. As a result, it has recently attracted a lot of interest as an active component towards pathogen inhibition. The aim of this paper is to prepare graphene oxide sheets, with two different oxygen concentrations of 15% and 39%, characterize them, and then investigate in vitro their antimicrobial efficacy in both Gram-positive and Gram-negative bacteria. In particular, GO sheets are synthesized via the Hummer’s method and subsequently, electron microscopy (SEM), X-ray diffraction (XRD) and Raman spectroscopy are used to investigate the GO sheet morphology and structure, while Energy Dispersive X-ray Spectroscopy (EDS) is employed for elemental analysis. Subsequently, clinical isolates of Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa are incubated with different concentrations of GO sheets, ranging from 0.25 mg/ml to 1.5 mg/ml for 24 h at 37 °C to evaluate the antimicrobial effect. The results confirmed that that Gram positive bacteria are more sensitive to GO, while GO with a higher oxygen content exhibits increased antibacterial activity.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
