Synthesis and characterization of gold nanoparticles using fruit extract of Crescentia cujete L

Fauzan Amin,Nada Morisca,Micha Mahardika

doi:10.24114/jpkim.v11i3.15737

Abstract

Nanoparticles play important role in biotechnology such as food and drug industries. Gold nanoporticles(Au-NPS) have been wdely used in any drug therapies like drug delivery system for cancer, tumor, and diabetes treatment. Recently, Au-NPS have been devoleped to increase drug selectivity between tumor and normal cells. In the present studies, we use the fresh fruit ekstract (FFE) of crescentia cujete L mediated blue green alga for the synthesis of Au-NPS. The characterization of Au-NPS was carried out by using UV-Vis spectroscopy, Fourier transform infrared spectroscopy (FTIR), and Transmission Electron spectroscopy (TEM). UV-VIS spectrometry indicated formation of nanoparticles which produces an intense absorbance peak at 531 nm. FTIR reveales the functional group involved in reduction and stabilization of Au-NPS. TEM have shown the morphology of Au-NPS with mean size 10,11 nm. Keywords: Crescentia cujete; gold nanoparticles; green alga

Highlights

Nanotechnology, a combination of principles involving biology, physical and chemical
We have studied the synthesis of AuNPs using fresh fruit ekstract (FFE)
Extraction and synthesis Dried green algae of S. platensis (1 g) powder was added to 10 mL of aquadest and The mixture was centrifuged at 5000 rpm for 10 min (Suganya et al 2014)

Summary

Introduction

Nanotechnology, a combination of principles involving biology, physical and chemical. Nanoparticles have a special place in nonotechnologi due to which they have been widely used in daily lives like detecting environmental toxic metals, diagnostic imaging, biosensing, cancer therapeuticsand targeted drug delivery. The synthesis of Au-NPs has been carried out using microwave irradiation, electrochemical, thermal decomposition and chemical reduction. Blue green alga Spirulina platensis has been used in synthesis of AuNPs with smaller size (average 5 nm) and uniform shape (Suganya et al 2015). Seetharaman et al (2017) have studied the fabrication of gold nanoparticles using an aqueous leaf extract of Crescentia cujete and the potency of its fruit was ignored. Synthesis and characterization of gold nanoparticles using fruit extract of crescentia cujete L from crescentia cujete and blue green alga to degrade the toxic chemicals may be produced during reduction process

Materials and Methods

Results

Discussion

Conclusion