Synthesis and characterization of ginger (Z. officinale) extract mediated iron oxide nanoparticles and its antibacterial activity

Abstract

Abstract Green synthesis is one of the simple, eco- friendly and cost effective method of nanoparticles synthesis. Different biological things are used in this method. The iron oxide nanoparticles which are generally synthesized by physical and chemical methods are also synthesized by using ginger (Zingiber officinale) extract. Ferric chloride was used as a precursor and ginger extract acts as reducing agent. The formation of iron oxide nanoparticles were characterized by UV– visible spectroscopy, Fourier transform infrared spectroscopy (FTIR) X- ray diffraction technique (XRD) and scanning electron microscopy (SEM). The iron oxide nanoparticles showed characteristic peak at 406 nm. The different functional groups attached to it were analyzed by FTIR spectroscopy. In X-ray diffraction analysis of nanoparticles, it showed highest peak at (3 1 1) crystal plane with 2 θ value 32.43. The stabilized and cubic structure of iron oxide nanoparticles were determined by SEM analysis. The synthesized nanoparticles from ginger extract have antibacterial activity against Gram negative bacteria E. coli with zone of inhibition 22 mm diameters. The synthesized iron oxide nanoparticles are expected to have potential antioxidant and antifungal activity. This new approach of nanoparticles synthesis is found to be more convenient than any other method.