Synthesis and characterization of FeO-MnO magnetic nanoparticles in vitro antioxidant and antibacterial studies

Abstract

Transition metal oxides of FeO-MnO magnetic hetero nanostructures were prepared by chemical co-precipitation method using a biological surfactant Deoxyribonucleic Acid (DNA). The characterization of the nanoparticles was performed by Energy-dispersive X-ray spectroscopy (EDS), X-Ray Diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), Scanning Electron Microscope (SEM), and vibrating-sample magnetometer (VSM). Elemental composition was confirmed by EDS.XRD analysis gave information about the crystallinity and two different phases present in the sample. Optical studies were done using FTIR spectroscopy. The sample morphology was explored in SEM images. Magnetic nature confirmed using VSM analysis. Antimicrobial activities of the samples were investigated against bacteria Staphylococcus aureus(S aureus) and Escherichia Coli (E Coli) were swabbed using agarwell diffusion method. The antioxidant properties of the samples were assessed by using DPPH (2, 2-diphenyl-1-picryl-hydrazyl-hydrate) assay, Hydrogen peroxide, hydroxyl, and superoxide free radicals. The synthesized nanoparticles were shown potential activity in scavenging in vitro DPPH assay. The synthesized nanocomposites having reduced size exhibit better scavenging activity and act as good antioxidant compared to others.