Abstract
AbstractN‐Benzylacrylamide (1) and N‐(3‐aminopropyl)methacrylamide hydrochloride (2) were copolymerized to give poly[N‐benzylacrylamide‐co‐N‐(3‐aminopropyl)methacrylamide hydrochloride] (3). The reactivity ratios r1 and r2 were found to be r1 = 0,87 and r2 = 0,66 in which r1r2 < 1 indicate a statistical copolymer composition. Dehydrochlorination of the copolymer liberated primary amino groups to which peptide chains were grafted by reaction with L‐alanine‐NCA. The solubility of the resulting graft copolymers (6) in trifluoroacetic acid allowed the characterization of the products both by NMR and polarimetry. These methods and IR spectroscopy showed that the primary amino groups have only partially participated in initiating the NCA polymerization. The length of grafted peptide chains was found to be always higher than the one calculated from the ratio [NCA]/[NH2].
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
