Abstract

A convenient and green synthetic route using calcium ion induction was first used to prepare peanut protein isolate (PPI) nanoparticles.

Highlights

  • The term “nanoparticles” in the pharmaceutical eld is generally employed to describe colloidal particles which are substantially spherical and have a diameter ranging from 1 nm to 1000 nm.[1]

  • Through dynamic light scattering (DLS) and transmission electron microscopy (TEM), the role of each procedure in the formation of nanoparticles was systematically investigated by means of particle size, size distribution, and morphology observation

  • peanut protein isolate (PPI) nanoparticles still display a good state in terms of size and morphology

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Summary

Introduction

The term “nanoparticles” in the pharmaceutical eld is generally employed to describe colloidal particles which are substantially spherical and have a diameter ranging from 1 nm to 1000 nm.[1]. Protein is ideal for nanoparticle preparation due to its multilevel construction, biodegradable, non-toxic, and non-immunogenic nature, patient tolerability and abundant source.[8] There are lots of different kinds of protein nanoparticles reported, such as bovine serum albumin,[9,10] casein,[11,12] collagen,[13] b-lacto globulin[14,15] and other animal proteins.[16] reports about the application of plant protein in the preparation of nanoparticles as the matrix material are relatively few. The plant proteins which have been applied in the preparation of nanoparticles are only silk, soy protein isolates or zein etc.[7,17,18] Peanut protein is a highly nutritious vegetable protein resource, ranking no. 3 of plant protein sources in the world, accounting for 11% of total protein.[19] its application for the preparation of nanoparticle, carrying and delivery peanut bioactive compounds, is still blank

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